I got a MiSTer not too long ago and have been working on it lately. So far, I've got NES, Genesis, Game Boy, SNES, Master System, Colecovision, Turbografx-16, and Vectrex games working. I'm having problems with getting Atari 2600 games working, which I looked forward to playing. I can't get the wi-fi to work either.
Regardless of the issues I've had, this seems like it's going to be a great option in the long term if you're autistic over accuracy and don't want a bunch of different game systems and accessories taking up space.